Prebichol (Obeticholic Acid) is prescribed for Primary Biliary Cholangitis (PBC) in the following scenarios:
- Prebichol can be taken with or without food.
- If taken alongside bile-acid binding resins, the obeticholic acid dose should be separated by at least 4 hours.
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Obeticholic acid is a Farnesoid X receptor (FXR) agonist. FXR regulates key genes involved in bile acid synthesis, lipid metabolism, and glucose control. By activating FXR, obeticholic acid reduces bile acid production in the liver and enhances bile acid transport, reducing liver exposure to bile acids.
Take FXR 10MG as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Prebichol should not be used in patients with complete biliary obstruction.
Store in a cool and dry place away from sunlight